Progressive Diplopia and Facial Weakness in a 62-Year-Old Woman

Progressive Diplopia and Facial Weakness in a 62-Year-Old Woman 

Diplopia progressiva e fraqueza facial em uma mulher de 62 anos de idade.

Monika R. Kolloori, MD, Luis J. Mejico, MD, Joseph Corbo, MD, PhD, Aseem Sharma, MD, Melissa W. Ko, MD 

Dr. Kolloori: 
A 62-year-old woman presented to a local emergency department with horizontal diplopia that she first noted upon awakening the previous day. She had experienced a mild headache the prior evening but was otherwise well and denied any constitutional symptoms, concurrent or recent illnesses, jaw claudication, or eye pain. She had a history of hypercholesterolemia. Physical examination revealed normal vital signs. The patient’s visual acuity, intraocular pressures, and funduscopy were normal, and she had a mild abduction deficit of the left eye. Hematologic studies including complete blood count, metabolic panel, and sedimentation rate were normal. Noncontrast computed tomography (CT) of the head and magnetic resonance imaging (MRI) of the brain with and without contrast were performed.

Este artigo aborda a doença de Lyme, transmitida pelo carrapato e que provoca entre outras coisas febre, calafrios, fadiga, dores no corpo e dor de cabeça pode acompanhar a erupção cutânea, dor nas articulações, inflamação ocular. Causada pela bactéria Borrelia burgdorferi (http://www.minhavida.com.br/saude/temas/doenca-de-lyme). Este artigo aborda alguns outros sintomas da doença de Lyme em uma mulher de 62 anos, que muitas vezes são confundidos com casos de linfoma.

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Ebola and the need for restructuring pharmaceutical incentives.

Ebola and the need for restructuring pharmaceutical incentives.

Ebola e a necessidade de reestruturação dos incentivos farmacêuticos.

Abraar Karan1, Thomas Pogge2

1David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
2Yale University, Department of Philosophy, New Haven, CT, USA

The Ebola outbreak in West Africa has claimed the lives of over 9000 people largely due to a combination of poor health care infrastructure in affected countries, traditional beliefs and cultural practices, including the consumption of bushmeat and certain burial rituals that have amplified transmission, and the lack of therapeutic interventions such as medications and vaccinations [1,2].
Ebola virus was discovered in 1976, and since then there have been over 30 outbreaks, the majority occurring in Sub-Saharan Africa, yet development of medications has been negligible [3]. Moreover, while the current epidemic has spurred a new race to develop Ebola vaccines and treatment
regimens, the current patent system makes it unlikely that people in the most afflicted nations will have access to such vaccines or medications when they are brought to market without the assistance of development aid initiatives from the United Nations (UN), World Health Organization, the
GAVI Alliance and other multinational global entities.

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